Long extrachromosomal circular DNA (leccDNA) regulates several biological processes such as genomic instability, gene amplification, and oncogenesis. The identification of leccDNA holds significant ...

Mitochondrial transcription factor A (TFAM) employs DNA bending to package mitochondrial DNA (mtDNA) into nucleoids and recruit mitochondrial RNA polymerase (POLRMT) at specific promoter sites, light ...

－より高い分解能での遺伝子空間分布解析が可能に－ 理化学研究所（理研）開拓研究本部新宅マイクロ流体工学理研白眉研究チームの小口祐伴研究員、新宅博文理研白眉研究チームリーダー、東京大学大学院理学系研究科の上村想太郎教授は、「DNAバー ...

In 1953 James Watson and Francis Crick published the molecular structure of the biological hereditary material deoxyribonucleic acid (DNA) whose famous double-helical structure is now imprinted in the ...

In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in ...

For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...

DNA contains foundational information needed to sustain life. Understanding how this information is stored and organized has been one of the greatest scientific challenges of the last century. With ...

Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.